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Differential expression and ser897 phosphorylation of striatal N-methyl-d-aspartate receptor subunit NR1 in animal models of Parkinson's disease

✍ Scribed by Ranjita Betarbet; Olga Poisik; Todd B. Sherer; J.Timothy Greenamyre

Book ID: 116458189
Publisher: Elsevier Science
Year: 2004
Tongue: English
Weight: 926 KB
Volume: 187
Category: Article
ISSN: 0014-4886
DOI: 10.1016/j.expneurol.2003.12.012

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## Abstract Serine racemase (SR) is responsible for the biosynthesis of D‐serine (D‐Ser), an endogenous co‐agonist for the glycine (Gly)‐binding site on __N__‐methyl‐D‐aspartate (NMDA) receptors, from L‐Ser in the brain. We have previously demonstrated high expression of SR by chondrocytes in carti

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