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Differential expression and functional relevance of the death receptors CD95, DR4, and TNF-R1 in parietal and chief cells

✍ Scribed by Neu, Bruno; Hermuth, Hadda; Vaupel, Wolfgang; Classen, Meinhard; Schepp, Wolfgang


Book ID
123373301
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
199 KB
Volume
118
Category
Article
ISSN
0016-5085

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## Abstract Mice defective in Fas‐mediated apoptosis (__lpr__ phenotype) have an intrinsic B cell abnormality that predisposes them to autoantibody production. To investigate potential roles for the Fas receptor (FasR) in B cell tolerance, FasR expression and function were evaluated at different st