Differential electrophysiological effects of 3-PPP and its enantiomers on dopamine autoreceptors and postsynaptic receptors
β Scribed by Debra A. Bergstrom; Joanne H. Carlson; Susan D. Bromley; David M. Jackson; Judith R. Walters
- Book ID
- 115879819
- Publisher
- Elsevier Science
- Year
- 1986
- Tongue
- English
- Weight
- 872 KB
- Volume
- 124
- Category
- Article
- ISSN
- 0014-2999
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract The effects of the enantiomers of 3βhydroxyphenolβNβnβpropylpiperidine (3βPPP) at dopamine (DA) synthesis modulating autoreceptors, measured as DOPA accumulation after decarboxylase inhibition, were assessed in vivo and in rat striatal slices. In vivo, (+)β3βPPP inhibited DOPA accumulat
Effect of 3-PPP, a putative dopamine autoreceptor agonist, on [3H]ligand binding to dopamine receptors of calf and rat striatum. Drug Dev. Res. 3:177-184, 1983. 3-(3-Hydroxyphenyl)-N-n-propyliperidine (3-PPP) is most effective in inhibiting I3HJapomorphine binding in rat striatal membranes, with Ki