Differential effects on phospholipid phase transitions produced by structurally related long-chain alcohols

On a possible invariance of a transition

On a possible invariance of a transition structure to the effects produced by ancillary H-bonding molecules: Modeling the effects of Ser-48 in the hydride-transfer step of liver alcohol dehydrogenase

✍ R. Cárdenas; J. Andrés; J. Krechl; M. Campillo; O. Tapia 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 1020 KB

The influence of a hydroxyl group simulating Ser-48 in the hydride-transfer step characteristic of liver alcohol dehydrogenase is studied on the hydride-transfer reaction as modeled by a methanolate anion interacting with a cyclo propenyl cation. It is shown first that this is an adequate model by c