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Differential effects of the tumor promoter phorbol-12-myristate-13-acetate on the morphological and biochemical differentiation of N-18 mouse neuroblastoma cells

✍ Scribed by Alice Y.-C. Liu; Kuang Yu Chen

Publisher
John Wiley and Sons
Year
1985
Tongue
English
Weight
743 KB
Volume
125
Category
Article
ISSN
0021-9541

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✦ Synopsis

The phorbol ester tumor promoter phorbol-12-myristate-13-acetate (PMA) was found to have differential inhibitory effects on the expression of morphological and biochemical differentiation of N-18 mouse neuroblastoma cells. PMA completely inhibited neurite extension and associated growth characteristics and partially inhibited the increased expression of RI CAMP-binding protein;

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