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Differential effects of streptozotocin-induced diabetes on expression of hepatic ABC-transporters in rats

✍ Scribed by Willie M. van Waarde; Henkjan J. Verkade; Henk Wolters; Rick Havinga; Juul Baller; Vincent Bloks; Michael Müller; Pieter J.J. Sauer; Folkert Kuipers

Book ID
119756588
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
342 KB
Volume
122
Category
Article
ISSN
0016-5085

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Impact of Acute Streptozotocin-Induced D
Impact of Acute Streptozotocin-Induced Diabetes on ABC Transporter Expression in Rats
✍ Gregory J. Anger; Lilia Magomedova; Micheline Piquette-Miller 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 392 KB

## Abstract Hepatic ABC efflux transporters control the cellular uptake (in basolateral membranes) and excretion (in apical membranes) of many substrates. Since type‐1 diabetes mellitus (T1DM) is associated with altered hepatobiliary excretion of many endogenous and exogenous substances, we examine