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Differential effects of stereochemistry and C-4 substituents on the enantioselectivity of PLE and PPL catalyzed hydrolysis of 3,4-disubstituted β-lactams

✍ Scribed by Amit Basak; Tapan Mahato; Gautam Bhattacharya; Ballari Mukherjee

Publisher
Elsevier Science
Year
1997
Tongue
French
Weight
138 KB
Volume
38
Category
Article
ISSN
0040-4039

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✦ Synopsis

Pig Liver Esterase (PLE) and Pig Pancreas Lipase (PPL) catalysed hydrolysis of (±)trans-3-carbethoxy and (±)cis-3-acetoxymethyl 4-substituted B-lactams revealed interesting-dependence on C-3, C-4 stereochemistry and nature of C-4 substituents.©1997, ElsevierScienceL~.Allrigh~ ~served.

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