Differential Effects of NOD2 Variants on Crohn's Disease Risk and Phenotype in Diverse Populations: A Metaanalysis
β Scribed by Economou, Michael; Trikalinos, Thomas A.; Loizou, Konstantinos T.; Tsianos, Epameinondas V.; Ioannidis, John P.A.
- Book ID
- 120548583
- Publisher
- Nature Publishing Group
- Year
- 2004
- Tongue
- English
- Weight
- 270 KB
- Volume
- 99
- Category
- Article
- ISSN
- 0002-9270
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## Background: Nod2 mutations are associated with crohn's disease (cd) in caucasian clinic-based cohorts. data from population-based cohorts are limited. clinic-based studies may overestimate this association. genotype-phenotype relationships are yet to be assessed using the montreal classification
## Background: Distinct crohn's disease (cd) phenotypes correlate with antibody reactivity to microbial antigens. we examined the association between antibody response to 2 new flagellins called a4-fla2 and fla-x, anti-saccharomyces cerevisiae antibodies (asca), anti-neutrophil cytoplasmic antibodi