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Differential effects of melatonin on amyloid-β peptide 25–35-induced mitochondrial dysfunction in hippocampal neurons at different stages of culture

✍ Scribed by Weiguo Dong; Fang Huang; Wenguo Fan; Shaowu Cheng; Yue Chen; Wenguang Zhang; Hong Shi; Hongwen He

Book ID
111264721
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
581 KB
Volume
48
Category
Article
ISSN
0742-3098

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## Abstract The aim of this study was to assess the effect of the β‐amyloid fragment Aβ~25–35~ on mitochondrial structure and function and on the expression of proteins associated with the mitochondrial permeability transition pore (MPTP) in rat hippocampal neurons. Ninety clean‐grade Sprague–Dawle