Effect of Arsenite on Urea Production by
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Adolfo Sierra-Santoyo; Ascención Hernández; María de Lourdes López; Tomás Mendoz
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Article
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1996
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John Wiley and Sons
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English
⚖ 687 KB
Urea cycle is a hepatic metabolic pathway involving five enzymes and several intermediary metabolites and can be altered by different chemicals. To investigate the effect of arsenic, an ubiquitous hepatotoxic agent, on urea production we exposed long-term cultures of adult rat hepatocytes, which pro