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Differential Effects of High-Dose Gamma Irradiation on the Production of Transforming Growth Factor-Beta in Fresh and Established Human Ovarian Cancer

โœ Scribed by Alessandro D. Santin; John C. Hiserodt; Philip J. DiSaia; Sergio Pecorelli; Gale A. Granger


Book ID
115616869
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
91 KB
Volume
61
Category
Article
ISSN
0090-8258

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Tumor cells from 7 freshly isolated human ovarian tumors and 2 continuous human ovarian cancer cell lines were analyzed for their surface expression of MHC class-I, class-ll and ICAM-I surface antigens before and after exposure to y-irradiation and/or the cytokines TNF-a plus IFN-y. All 7 fresh tumo