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Differential effects of guanine nucleotides on the first step of VIP and glucagon action in membranes from liver cells

โœ Scribed by Brigitte Amiranoff; Marc Laburthe; Gabriel Rosselin


Book ID
118314891
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
341 KB
Volume
96
Category
Article
ISSN
0006-291X

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This study was undertaken to investigate the effect of experimental diabetes on the early steps of glucagon action. The binding of glucagon and glucagon-stimulated cyclic AMP accumulation in the presence of a potent phosphodiesterase inhibitor (IBMX, 0.1 mmol/l) were studied in liver cells isolated