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Differential effects of ganodermic acid S on the thromboxane A2-signaling pathways in human platelets

✍ Scribed by Chen-Yi Su; Ming-Shi Shiao; Cheng-Teh Wang


Book ID
113994475
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
409 KB
Volume
58
Category
Article
ISSN
0006-2952

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Picotamide (G 137), a new non prostanoid inhibitor of in vitro arachidonic acid induced platelet aggregation, has been further characterized in in vitro and ex vivo studies. When whole blood was activated with collagen in the presence of picotamide 5 x 10(-4) M, thromboxane B2 production was decreas