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Differential effects of fumonisin B1on cell death in cultured cells: the significance of the elevated sphinganine

✍ Scribed by Chang-Hun Yu; Yong-Moon Lee; Yeo-Pyo Yun; Hwan-Soo Yoo


Publisher
Springer
Year
2001
Tongue
English
Weight
943 KB
Volume
24
Category
Article
ISSN
0253-6269

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Fumonisins are mycotoxins produced by Fusarium verticillioides. The toxic effects of fumonisin B 1 (FB 1 ) at the cellular level consist of a mixture of both necrosis and apoptosis. We studied the effect of FB 1 in human lung fibroblasts (NHLF) and human kidney epithelial cells (RPTEC) in primary cu