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Differential effects of endocannabinoids on [3H]-GABA uptake in the rat globus pallidus

✍ Scribed by Katerina Venderova; Timothy M. Brown; Jonathan M. Brotchie


Book ID
116458513
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
98 KB
Volume
194
Category
Article
ISSN
0014-4886

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The effect of carbachol on the spontaneous release of 3 H-GABA was investigated on rat globus pallidus (GP) slices. Carbachol dose-dependently enhanced the release of 3 H-GABA. The carbachol (5 3 10 24 M) induced 3 H-GABA release is mediated by muscarinic receptors since atropine (10 26 M), pirenzep