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Differential Effects of Continuous and Intermittent 17β-Estradiol Replacement and Tamoxifen Therapy on the Prevention of Glomerulosclerosis: Modulation of the Mesangial Cell Phenotype in Vivo

✍ Scribed by Michael Karl; Mariana Berho; Judith Pignac-Kobinger; Gary E. Striker; Sharon J. Elliot

Book ID
117970530
Publisher
American Society for Investigative Pathology
Year
2006
Tongue
English
Weight
754 KB
Volume
169
Category
Article
ISSN
0002-9440

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## Abstract A human ovarian adenocarcinoma cell line (PE04) has been established as a xenograft in nude mice. __In vitro__, this cell line is estrogen receptor (ER)‐positive and its growth is stimulated by 17 β‐estradiol at concentrations between 10^−12^ and 10^−6^ M. When xenografted, PE04 cells r