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Differential effects of arsenic trioxide on chemosensitization in human hepatic tumor and stellate cell lines

✍ Scribed by Rangwala, Fatima (author);Williams, Kevin P. (author);Smith, Ginger R. (author);Thomas, Zainab (author);Allensworth, Jennifer L. (author);Lyerly, H. K. (author);Diehl, Anna M. (author);Morse, Michael A. (author);Devi, Gayathri R. (author)

Book ID
119897445
Publisher
BioMed Central
Year
2012
Tongue
English
Weight
524 KB
Volume
12
Category
Article
ISSN
1471-2407

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## Abstract Arsenic trioxide (ATO) has been recommended for the treatment of refractory cases of acute promyelocytic leukemia (APL). Recent studies in our laboratory indicated that oxidative stress plays a key role in ATO‐induced cytotoxicity in human leukemia (HL‐60) cells. In the present investig