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Differential effects of acute cannabinoid drug treatment, mediated by CB1receptors, on the in vivo activity of tyrosine and tryptophan hydroxylase in the rat brain

✍ Scribed by David Moranta; Susana Esteban; JesúsA. García-Sevilla

Publisher: Springer-Verlag
Year: 2004
Tongue: English
Weight: 596 KB
Volume: 369
Category: Article
ISSN: 0028-1298
DOI: 10.1007/s00210-004-0921-x

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## Abstract The cannabinoids (CB) modulate the extracellular signal‐regulated kinase (ERK), leading to various forms of plasticity in the brain. Little is known, however, on the in vivo short‐ and long‐term activation and regulation of the components of mitogen‐activated protein kinase (MAPK)/ERK s