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Differential effect of ursodeoxycholate and its taurine conjugate on biliary transport maximum of bilirubin in the rat

✍ Scribed by J. Enrique; Sánchez Pozzi; Aldo D. Mottino; Alfonso Sisti; Marcelo G. Roma

Book ID
116018669
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
791 KB
Volume
57
Category
Article
ISSN
0024-3205

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✍ Pietro Invernizzi; Kenneth D. Setchell; Andrea Crosignani; Pier Maria Battezzati 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 180 KB 👁 2 views

The clinical effectiveness of ursodeoxycholate in the treatment of liver disease may be limited by its poor absorption and extensive biotransformation. Because in vitro and in vivo studies suggest that the more hydrophilic bile acid tauroursodeoxycholate has greater beneficial effects than ursodeoxy