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Differential effect of typical and atypical antipsychotic drugs on the suppressant action of 2-methylserotonin on medial prefrontal cortical cells: a microiontophoretic study

โœ Scribed by Charles R. Ashby Jr.; Emmeline Edwards; Kelly L. Harkins; Rex Y. Wang

Book ID
115882416
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
143 KB
Volume
166
Category
Article
ISSN
0014-2999

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Comparison of the effects of various typ
Comparison of the effects of various typical and atypical antipsychotic drugs on the suppressant action of 2-methylserotonin on medial prefrontal cortical cells in the rat
โœ Charles R. Ashby Jr.; Yoshio Minabe; Emmeline Edwards; Rex Y. Wang ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 767 KB

In this study, we report the effects of various typical and atypical antipsychotic drugs (APDs) on the suppressant action of microiontophoretically applied 2-methylserotonin (2-Me-5HT, a 5-HT3 agonist) on medial prefrontal cortical (mPFc) cells. The microiontophoresis of 2-Me-5HT (10-80 nA) produced