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Differential effect of sodium arsenite during the activation of human CD4+ and CD8+ T lymphocytes

✍ Scribed by Eda Patricia Tenorio; Rafael Saavedra


Book ID
116575818
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
876 KB
Volume
5
Category
Article
ISSN
1567-5769

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CD4, CD8 and CD45 regulate the coupling of the T-cell receptor complex (CD3-TCR) to tyrosine kinase activation and phosphorylation of key substrates such as phospholipase C gamma 1. CD4 and CD8 contribute to activation signals through their cytoplasmic association with p56lck. Expression of the zeta