Differential effect of interferon on ornithine decarboxylase activation in quiescent Swiss 3T3 cells
β Scribed by E.J. Lee; P.C. Larkin; T. Sreevalsan
- Book ID
- 119406802
- Publisher
- Elsevier Science
- Year
- 1980
- Tongue
- English
- Weight
- 369 KB
- Volume
- 97
- Category
- Article
- ISSN
- 0006-291X
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## Abstract The addition of 50 ΞΌM exogenous putrescine to Swiss 3T3 cells during serum stimulation resulted in a sixfold increase in intracellular putrescine content and prevented the rise in ornithine decarboxylase activity normally seen in response to serum. SV3T3 cells had putrescine levels ten
## Abstract Quiescent 3T3 cells can be stimulated to enter S by defined factors. When used in combination, three polypeptide hormones (EGF, vasopressin, and insulin), or a tumor promotor and insulin, are very effective in stimulating DNA synthesis. Like serum, the defined factors also stimulate deo
## Abstract Recently, we have found that an increase in the intracellular level of cAMP acts as a mitogenic signal for Swiss 3T3 cells (Rozengurt et al., Proc. Natl. Acad. Sci. USA, 78:4392, 1981). The results presented in this paper demonstrate that addition of cAMPβelevating agents to confluent a