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Differential effect of catecholamines and MPP+ on membrane permeability in brain mitochondria and cell viability in PC12 cells

✍ Scribed by Chung Soo Lee; Jeong Ho Han; Yoon Young Jang; Jin Ho Song; Eun Sook Han

Book ID
117409699
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
175 KB
Volume
40
Category
Article
ISSN
0197-0186

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## Abstract A large body of experimental evidence supports a role for oxidative stress as a mediator of nerve cell death in Parkinson's disease. To better understand the cellular insult of oxidative stress on dopaminergic neurons, we studied the cytotoxic effect of the 1‐Methyl‐4‐phenyl‐1,2,3,6‐tet