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Differential dose delivery for cancers of the head and neck

โœ Scribed by Komanduri M. Ayyangar; Mohammed Mohiuddin


Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
619 KB
Volume
21
Category
Article
ISSN
0958-3947

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โœฆ Synopsis


A technique was developed for the treatment of head and neck cancers that employs differential dose delivery to primary and nodal areas while simultaneously correcting the dose delivered through various thickness of tissue in the field(s). Our technique modulates the intensity of the static lateral fields in three dimensions utilizing data acquired from a pre-treatment CT scan. This technique has been used to treat patients with various cancers of the head and neck. All patients tolerated treatment well with no observed increase in acute normal tissue reactions.


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Objectives/Hypothesis: The optimal concurrent chemoradiotherapy regimen for definitive treatment of locoregionally advanced head and neck cancer remains to be determined. The present investigation reports toxicities, disease control, patterns of failure, and survival outcomes in a large mature cohor