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Differential distribution, affinity and plasticity of dopamine D-1 and D-2 receptors in the target sites of the mesolimbic system in an animal model of ADHD

✍ Scribed by Margaret P Carey; Linda M Diewald; Felice J Esposito; Mario P Pellicano; Ugo A Gironi Carnevale; Joseph A Sergeant; Michele Papa; Adolfo G Sadile


Book ID
117346139
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
730 KB
Volume
94
Category
Article
ISSN
0166-4328

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## Abstract In this study we examined the selectivity of dopamine (DA) for rat striatal DA D~1~ and D~2~ receptors. In a Krebs‐HEPES buffer, the K~i~ values of DA for D~1~ binding sites (labelled with [^3^H]SCH23390) and D~2~ binding sites (labelled with [^3^H]spiroperidol) in striatal membranes am