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Differential diagnostic challenge of chronic neutrophilic leukemia in a patient with prolonged leukocytosis

✍ Scribed by Daniel Neureiter; Ralf Kemmerling; Matthias Ocker; Christoph Seidlhofer; Viktoria Faber; Markus Stöcher; Richard Greil; Otto Dietze


Book ID
107648013
Publisher
Springer-Verlag
Year
2008
Tongue
English
Weight
299 KB
Volume
1
Category
Article
ISSN
1865-5785

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We encountered a 67-year-old female with chronic neutrophilic leukemia (CNL). Cytogenetic study showed she had a deletion in the long arm of chromosome 20. This finding indicates that CNL, in this case, is a clonal disorder. Most CNL patients have normal karyotypes, and only four patients with cytog