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Differential changes in mRNAs encoding for preprotachykinin A and B after kainic acid-induced seizures in the rat

✍ Scribed by Romuald Bellmann; Christian Humpel; James E. Krause; Josef Marksteiner; Alois Saria; Dr. Güther Sperk


Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
353 KB
Volume
8
Category
Article
ISSN
0887-4476

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Kainic acid-induced seizures and brain d
✍ M. Berg; T. Bruhn; Aa. Frandsen; A. Schousboe; N. H. Diemer 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 901 KB

Seizure activity induced by kainic acid (KA) and subsequent neuronal death are thought to be associated with an increase in cytoplasmic free calcium ([Ca2+li) and can be prevented by N-methyl-D-aspartate (NMDA) antagonists. In addition to influx through receptor operated Ca2+ channels the increase i