Differential calcium-signaling pathways to BDNF and c-fos genes in mouse cerebellar granule cells
β Scribed by Masaru Yukimine; Akiko Tabuchi; Masaaki Tsuda
- Book ID
- 117364738
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- English
- Weight
- 128 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0168-0102
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π SIMILAR VOLUMES
## Abstract We have demonstrated previously in primary cultures of mouse cerebellar granule cells (CGCs) that endogenously synthesized pituitary adenylate cyclaseβactivating polypeptide (PACAP) contributes at least in part to the activityβdependent survival of CGCs (Tabuchi et al. [2001] Neurosci.
The altered kinetics of steady-state c-fos mRNA production in cultured cerebellar granule cells under excitotoxic conditions was investigated in neurons subjected to depolarising stimuli, namely, high KCl and L-glutamate (Glu), in which Ca 2Ψ influx occurs by differing routes. Increases in intracell