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Differential association of the PTPN22 coding variant with autoimmune diseases in a Dutch population

✍ Scribed by Zhernakova, A; Eerligh, P; Wijmenga, C; Barrera, P; Roep, B O; Koeleman, B P C


Book ID
110037730
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
75 KB
Volume
6
Category
Article
ISSN
1466-4879

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## Background: The PTPN22 gene is an important risk factor for human autoimmunity. The aim of this study was to evaluate for the first time the role of the R263Q PTPN22 polymorphism in ulcerative colitis (UC) and Crohn's disease (CD), and to reevaluate the association of the R620W PTPN22 polymorph