Differential antiinflammatory and antinociceptive effects of the somatostatin analogs octreotide and pasireotide in a mouse model of immune-mediated arthritis

Antiinflammatory and analgesic effects o

Antiinflammatory and analgesic effects of somatostatin released from capsaicin-sensitive sensory nerve terminals in a Freund's adjuvant–induced chronic arthritis model in the rat

✍ Zsuzsanna Helyes; Árpád Szabó; József Németh; Balázs Jakab; Erika Pintér; Ágnes 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 243 KB 👁 2 views

## Abstract ## Objective We previously demonstrated that somatostatin (SOM) released from the activated peripheral terminals of capsaicin‐sensitive primary sensory neurons inhibits acute inflammation and nociception. This study was undertaken to examine this systemic “sensocrine” function of neuro