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Differential alterations in the activity of matrix metalloproteinases within the nervous tissue of dogs in distinct manifestations of visceral leishmaniasis

✍ Scribed by Gisele F. Machado; Guilherme D. Melo; Olívia C. Moraes; Milena S. Souza; Mary Marcondes; Sílvia H.V. Perri; Rosemeri O. Vasconcelos


Book ID
116966719
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
570 KB
Volume
136
Category
Article
ISSN
0165-2427

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## Abstract Matrix metalloproteinases (MMPs) degrade the extracellular matrix and are implicated in the pathogenesis of several neurological diseases. Secreted in proforms, the MMPs require activation. Tissue inhibitors of matrix metalloproteinases (TIMPs) regulate the activity of MMPs. We investig