Tolerance and Specificity of Recombinant
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Maia T. Richardson; Nicola L. Pohl; James T. Kealey; Chaitan Khosla
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Article
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1999
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Elsevier Science
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English
⚖ 241 KB
Background: 6-Methylsalicylic acid synthase (MSAS), a fungal polyketide synthase from Penicillium patulum, is perhaps the simplest polyketide synthase that embodies several hallmarks of this family of multifunctional enzymes a large multidomain protein, a high degree of specificity toward acetyl-CoA