Differential activation by atrial and brain natriuretic peptides of two different receptor guanylate cyclases
โ Scribed by Chang, Ming-shi; Lowe, David G.; Lewis, Martyn; Hellmiss, Renate; Chen, Ellson; Goeddel, David V.
- Book ID
- 109761014
- Publisher
- Nature Publishing Group
- Year
- 1989
- Tongue
- English
- Weight
- 678 KB
- Volume
- 341
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/341068a0
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
A line of kidney cells (PK1) which does not possess measurable ANP binding but has an active particulate guanylate cyclase has been identified. The physical characteristics of this enzyme were compared with those of particulate guanylate cyclase and ANP receptors isolated from rat lung. Although rec
The putative 'second messenger' of certain atrial natriuretic factor (ANF) signal transductions is cyclic GMP. Recently, we purified a 180-kDa protein, apparently containing both ANF receptor and guanylate cyclase activities, and hypothesized that this is one of the cyclic GMP transmembrane signal t
The 98 amino acid (a.a.) N-terminus of the 126 a.a. atrial natriuretic factor (ANF) prohormone contains three peptides consisting of a.a. 1-30 (proANF 1-30), a.a. 31-67 (proANF 31-67) and a.a. 79-98 (proANF 79-98) with blood pressure lowering, sodium and/or potassium excreting properties similar to