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Differential activation and inactivation of benzo[a]pyrene in various hepatoma cell lines

✍ Scribed by S. Hesse; O. Cumpelik; E. Roscher; F.J. Wiebel


Book ID
113251630
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
88 KB
Volume
203
Category
Article
ISSN
0165-1161

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## Abstract We studied the genotoxic potential of a carcinogen in the human hepatoma cell line, HepG2 and in primary rat hepatocyte culture. HepG2 is a well differentiated human hepatoblastoma cell line with biotransforming capacity. Rat hepatocytes were obtained by the standard two‐step in situ pe