Differential accumulation of non-transferrin-bound iron by cardiac myocytes and fibroblasts
✍ Scribed by Ying Liu; Joel G. Parkes; Douglas M. Templeton
- Book ID
- 117142347
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 469 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0022-2828
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## Abstract Non‐transferrin bound iron (NTBI) is commonly detected in patients with systemic iron overload whose serum iron‐binding capacity has been surpassed. It has been perceived as an indicator of iron overload, impending organ damage and a chelation target in poly‐transfused thalassemia patie
## Abstract Reticulocytes suspended in low ionic strength media such as isotonic sucrose solution efficiently take up non‐transferrin‐bound iron and utilize it for heme synthesis. The present study was undertaken to determine how such media facilitate iron utilization by the cells. The effects of c