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Differential accumulation of advanced glycation end products in the course of diabetic retinopathy

✍ Scribed by H.-P. Hammes; A. Alt; T. Niwa; J. T. Clausen; R. G. Bretzel; M. Brownlee; E. D. Schleicher


Publisher
Springer
Year
1999
Tongue
English
Weight
720 KB
Volume
42
Category
Article
ISSN
0012-186X

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## Abstract Advanced glycation end‐products (AGE) play a role in the pathogenesis of several diseases, including diabetic complications and atherosclerosis. In atherosclerotic lesions of human aortas, AGE are localized in the extracellular matrix and intracellularly in foam cells. Two interpretatio