Differential ability of two adult molluscan neurons to regenerate electrical synapses
โ Scribed by Bulloch, A. G. M.
- Book ID
- 102544942
- Publisher
- John Wiley and Sons
- Year
- 1985
- Tongue
- English
- Weight
- 468 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0022-3034
No coin nor oath required. For personal study only.
โฆ Synopsis
The ability of two electrical synapses (neuron L4-R4 and neuron L19-R19) to regenerate in the adult Helisoma nervous system was examined. The L4-R4 electrical connection exhibited rapid restoration to 50% of normal strength, whereas L19-R19 reconnection was weak or absent. This disparity is attributable to the inability of neuron 19 to sprout effectively across a crush site in the buccal commissure, although peripheral sprouting was pronounced. The factors which underlie the inability of neuron 19 (but not neuron 4) to sprout into a central environment are unknown, but dictate differential synapse restoration in this adult nervous system.
๐ SIMILAR VOLUMES
A segment of tibial nerve was autografted to the right corpus striatum of deeply anesthetized adult rats; the distal graft was left beneath the scalp. Horseradish peroxidase (HRP) conjugates were injected into the distal graft after 2-30 weeks, and the animals were killed 2-3 days later. Small numbe