𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Differential abilities of phorbol esters in inducing protein kinase C (PKC) down-regulation in noradrenergic neurones

✍ Scribed by P Kotsonis; L Funk; C Prountzos; L Iannazzo; H Majewski


Book ID
110005474
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
213 KB
Volume
132
Category
Article
ISSN
0007-1188

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Induction of protein kinase C down-regul
✍ Michel Savart; Pascale Letard; Sandrine Bultel; Andre Ducastaing 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 French ⚖ 505 KB

## Abstract Using a calpain/protein kinase C (PKC) complex, we were able to reproduce, __in vitro__, the induction of PKC down‐regulation by the phorbol ester 12‐O‐tetradecanoyl‐phorbol‐13‐acetate (TPA) which had been previously observed in cells. We show that TPA initiates this phenomenon by promo

Protein kinase C activation and down-reg
✍ Jari E. Heikkilä; Göran Åkerlind; Karl E. O. Åkerman 📂 Article 📅 1989 🏛 John Wiley and Sons 🌐 English ⚖ 933 KB

The role of protein kinase C activation in changes in muscarinic receptor functions and in the appearance of biochemical properties characteristic of neuronal cells was studied in SH-SY5Y human neuroblastoma cells induced to differentiate with the phorbol ester 12-O-tetradecanoylphorbol-13-acetate (

Calphostin C induces tyrosine dephosphor
✍ Shan-Chih Lee; Shiaw-Der Yang 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 950 KB

The signal transduction mechanism of protein kinase FA/GSK-3a by tyrosine phosphorylation in A431 cells was investigated using calphostin C as an inhibitor for protein kinase C (PKC). Kinase F A / C S K -~~ could be tyrosine-dephosphorylated and inactivated to -10% of control in a concentration-depe

Arachidonic acid-induced down-regulation
✍ Keith L. Knutson; Margarethe Hoenig 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 954 KB

We have previously identified expression of multiple protein kinase C (PKC) isoforms in insulinomaderived beta-cells and whole islets. Both PKC 6 and PKC a appear to be the more abundantly expressed isoforms. in this report we studied the effects of arachidonic acid (AA) on the subcellular distribut