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Different treatment regimens and the development of tolerance to nicotine's anxiogenic effects

✍ Scribed by Elaine E Irvine; Survjit Cheeta; Melanie Marshall; Sandra E File

Book ID
114102232
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
191 KB
Volume
68
Category
Article
ISSN
0091-3057

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The effect of different chronic nicotine administration regimens on body weight and the development of tolerance was examined in female rats. Groups of animals were either treated with nicotine via a subcutaneous continuous release pellet or via two injections each day of either a high (5.6 mg/kg) o