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Different target antigens for T-cell subsets acting synergistically in vivo

✍ Scribed by Wolters, Emile A. J.; Benner, Robbert


Book ID
109719514
Publisher
Nature Publishing Group
Year
1980
Tongue
English
Weight
259 KB
Volume
286
Category
Article
ISSN
0028-0836

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## Abstract Naturally occurring CD4^+^ regulatory T cells can be identified on the basis of expression of CD25 and suppression of T cell responses __in vitro__ after TCR triggering. Here, we demonstrate that a CD134^+^ subset of CD4^+^CD25^+^ T cells in naive rats suppresses antigen‐specific T cell