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Different T cell subsets in the nodule and synovial membrane: Absence of interleukin-17A in rheumatoid nodules

✍ Scribed by Lisa K. Stamp; Andrea Easson; Ulrike Lehnigk; John Highton; Paul A. Hessian


Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
174 KB
Volume
58
Category
Article
ISSN
0004-3591

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## Abstract ## Objective Stromal cell–derived factor 1 (SDF‐1) is a potent chemoattractant for memory T cells in inflamed rheumatoid arthritis (RA) synovium. This study was undertaken to investigate the effect of interleukin‐17 (IL‐17) and CD40–CD40L interaction on SDF‐1 production in RA fibroblas