## Abstract The solidβstate and solution conformations of (+)βchelidonine (1), a biologically active alkaloid, were determined by Xβray diffraction and ^1^HβNMR spectroscopy, XβRay diffraction analysis revealed a conformer with B/C β__anti__βtypeβ __cis__ conjunction, a halfβchair of ring B, and a
Different solution and solid-state conformations of the antibiotic cycloheximide
β Scribed by Nigel B. Perry; John W. Blunt; Murray H. G. Munro
- Publisher
- John Wiley and Sons
- Year
- 1989
- Tongue
- English
- Weight
- 362 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0749-1581
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π SIMILAR VOLUMES
Nuclear magnetic resonance spectroscopy was combined with X-ray crystallography to determine the solution and solid-state conformations of glyburide (C23H28ClN305S). In solution, there is apparently free rotation about several of the single bonds. Crystals of glyburide belong to space group P2,ln wi
A dynamic process has been detected in the solution 13 C-NMR spectra of tBuΟͺSi(iPr)3 (4) in the temperature range Οͺ145 Β°C to Οͺ163 Β°C, the corresponding free energy of activation being 5.5 kcal mol Οͺ1 . Molecular mechanics calculations have identified three types of conformations that are markedly mo