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Different serum concentrations of steady-state valproic acid in two sustained-release formulations

โœ Scribed by NORIO YASUI-FURUKORI; MANABU SAITO; TAKU NAKAGAMI; TAKENORI NIIOKA; YASUSHI SATO; AKIRA FUJII; SUNAO KANEKO


Book ID
108962125
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
119 KB
Volume
61
Category
Article
ISSN
1323-1316

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## Abstract Divalproex sodium extendedโ€release (Depakote^ยฎ^ ER) is a once daily (QD) formulation for valproic acid that was developed to improve patient compliance and to reduce side effects compared with the standard twiceโ€daily (BID) delayed release (DR) formulation (Depakote^ยฎ^ tablets). However