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Different sensitivity to phorbol esters and pertussis toxin of bombesin- and platelet-derived growth factor-induced, phospholipase C-mediated hydrolysis of phosphoinositides in NIH/3T3 cells

✍ Scribed by Masahiko Hoshijima; Takashi Ueda; Yasuo Hamamori; Toshihiko Ohmori; Yoshimi Takai


Book ID
117058191
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
575 KB
Volume
152
Category
Article
ISSN
0006-291X

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Relationship of cytosolic ion fluxes and
✍ Dr. Martin Zagari; Marcy Stephens; H. Shelton Earp; Brian Herman πŸ“‚ Article πŸ“… 1989 πŸ› John Wiley and Sons 🌐 English βš– 816 KB

Platelet-derived growth factor (PDGF) and other agents that activate protein kinase C (PKC) rapidly alter cytosolic pH (pHJ and intracellular free calcium (Ca' +I,) in BALBk-3T3 fibroblasts. To define whether changes in pH, or [Ca++], are linked to PDGF-stimulated mitogenesis, these parameters were