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Different sensitivity of germinal center B cell-like diffuse large B cell lymphoma cells towards ibrutinib treatment

✍ Scribed by Zheng, Xiaohui; Ding, Ning; Song, Yuqin; Feng, Lixia; Zhu, Jun


Book ID
125400450
Publisher
BioMed Central
Year
2014
Tongue
English
Weight
525 KB
Volume
14
Category
Article
ISSN
1475-2867

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## Abstract Diffuse large B cell lymphoma (DLBCL) is an aggressive malignancy that accounts for nearly 40% of all lymphoid tumors. This heterogeneous disease can be divided into germinal center B cell‐like (GCB) and activated B cell‐like (ABC) subtypes by gene expression and immunohistochemical pro