Different sensitivities to competitive inhibition of benzodiazepine receptor binding of11C-iomazenil and11C-flumazenil in rhesus monkey brain
β Scribed by Osamu Inoue; Rie Hosoi; Kaoru Kobayashi; Takashi Itoh; Antony Gee; Kazutoshi Suzuki
- Publisher
- Springer Japan
- Year
- 2001
- Tongue
- English
- Weight
- 910 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0914-7187
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Quantitation of the PET benzodiazepine receptor antagonist, [ 11 C]Iomazenil, using low specific activity radioligand was recently described. The purpose of this study was to quantitate benzodiazepine receptor binding in human subjects using PET and high specific activity [ 11 C]Iomazenil. Six healt
By means of positron emission tomography the uptake and kinetics of N-(methyl-11C)clozapine in different brain regions have been studied in Rhesus monkeys. 11C-clozapine rapidly entered the brain and maximum radioactive uptake was seen 5-12 min after administration. Highest uptake was measured in th
Positron emission tomography was used to examine the in vivo binding of [ 11 C]raclopride to D 2 -dopamine (DA) receptors in the striatum of two Cynomolgus monkeys after a single dose of reserpine (1 mg/kg, i.v.). A Scatchard procedure was repeated five times to follow D 2 receptor density and appar