Different response patterns of several ligands at the sphingosine-1-phosphate receptor subtype 3 (S1P3)
β Scribed by M Jongsma; J Van Unen; PB Van Loenen; MC Michel; SLM Peters; AE Alewijnse
- Book ID
- 111218174
- Publisher
- Nature Publishing Group
- Year
- 2009
- Tongue
- English
- Weight
- 271 KB
- Volume
- 156
- Category
- Article
- ISSN
- 0007-1188
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
## Abstract G proteinβcoupled receptors (GPCRs) for lysophosphatidic acid (LPA) and sphingosine 1βphosphate (S1P) transduce signals to many functions of normal cells. Most human cancer cells upregulate S1P and LPA GPCRs, in patterns distinctive for each type of tumor. The findings that 1βalpha, 25β