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Different rate of chromosome breakage in human fibroblast strains after storage in liquid nitrogen

โœ Scribed by Casati, A.; Stefanini, M.; Giorgi, R.; Nuzzo, F.


Book ID
123575334
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
358 KB
Volume
275
Category
Article
ISSN
0921-8734

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The incidence of structural chromosome aberrations and the rate of sister chromatid exchanges (SCE) was investigated in lymphocyte cultures from a patient with typical Fanconi's anemia and his parents. The rate of SCEs was found to be normal. In experiments with the alkylating agent Trenimon the SCE