𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Different p53 mutation patterns in colorectal tumors from smokers and nonsmokers

✍ Scribed by Chi-Chou Huang; Ya-Wen Cheng; Meng-Cheng Chen; Yu-Shyang Lin; Ming-Chih Chou; Huei Lee


Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
168 KB
Volume
47
Category
Article
ISSN
0893-6692

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Have p53 gene mutations and protein expr
✍ Viviana Bazan; Manuela Migliavacca; Carla Tubiolo; Marcella Macaluso; Ines Zanna πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 251 KB

## Abstract p53 alterations are considered the most common genetic events in many types of neoplasms, including colorectal carcinoma (CRC). These alterations include mutations of the gene and/or overexpression of the protein. The aim of our study was to assess whether in 160 patients undergoing res

p53 mutations in childhood thyroid tumor
✍ Jan Smida; Horst Zitzelsberger; Albrecht M. Kellerer; Lars Lehmann; GΓΌnther Mink πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 French βš– 196 KB

Mutations in the p53 tumour-suppressor gene (exons 5-8) were investigated in 31 Belarussian childhood thyroid tumours (24 cases of papillary thyroid carcinoma, 3 benign tumours and 2 cases each of thyroiditis and goiter); 33 thyroid tumours from juveniles and adults without radiation exposures (25 c

Impact of mutant p53 functional properti
✍ Audrey Petitjean; Ewy Mathe; Shunsuke Kato; Chikashi Ishioka; Sean V. Tavtigian; πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 270 KB

The tumor suppressor gene TP53 is frequently mutated in human cancers. More than 75% of all mutations are missense substitutions that have been extensively analyzed in various yeast and human cell assays. The International Agency for Research on Cancer (IARC) TP53 database (www-p53.iarc.fr) compiles

Characterization of p53 gene mutations i
✍ Hisashi Tanaka; Ichio Shibagaki; Yutaka Shimada; Takashi Wagata; Masayuki Imamur πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 French βš– 557 KB

We screened 29 human esophageal squamous cell carcinoma (ESC) cell lines for mutations of the p53 gene through all coding exons and exon-intron junctions. Mutations were found in 22 cell lines (76%), consisting of 20 single-base substitutions, 2 small deletions and I single-base insertion. Out of 20

Nuclear accumulation of p53 in colorecta
✍ Upender Manne; Heidi L. Weiss; Russell B. Myers; Omar K. Danner; Cecilia Moron; πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 130 KB πŸ‘ 2 views

## BACKGROUND. Although several studies have been conducted to examine the role of p53 genetic abnormalities and their prognostic value in colorectal carcinoma, the incidence of nuclear accumulation of p53 and the prognostic importance of nuclear accumulation of p53 in African-American and white p