DIFFERENT MOLECULAR FORMS OF UNCOMPLEXED PROSTATE SPECIFIC ANTIGEN (PSA) SHOW SIMILAR IMMUNOREACTIVITIES

Different proportions of various prostat

Different proportions of various prostate-specific antigen (PSA) and human kallikrein 2 (hK2) forms are present in noninduced and androgen-induced LNCaP cells

✍ Abhay Kumar; Stephen D. Mikolajczyk; Timothy M. Hill; Lisa S. Millar; Mohammad S 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 229 KB

## BACKGROUND. Human prostate-specific antigen (PSA) and human kallikrein 2 (hK2) are expressed primarily by prostate epithelial cells. PSA and hK2 both exist as free protein and complexed with protease inhibitors (e.g., ␣1-antichymotrypsin, ACT) in serum. The expression of PSA and hK2 in LNCaP ce